Some research also talks about the importance of milk thistle in treating anxiety and depression – but we need more information on this before we come to conclusions. So it would be unusual for it alone to be responsible relieving gastro issues, but I sure wouldn't say … Taking milk thistle with this hepatitis C medication might increase levels of the drug in your blood plasma. Milk thistle as a beauty product When applied topically, milk thistle can reduce inflammation and improve skin conditions. In fact, in studies where high doses were used for long periods, only about 1% of people experienced side effects ( 1 ). As Little Bear said, milk thistle can cause a reaction in those with a rag weed allergy - like me. Also, as they said, it's use is for protecting and detoxing the liver. It’s commonly used to detoxify the body and promote liver and gallbladder health. Milk thistle (Silybum marianum) is an herbal remedy that has long been used in Iran. In this study, the effect of silibinin on Aβ-induced anxiety/depression-like behaviors in rats was investigated. Other uses not proven with research have included treating malaria , mushroom poisoning , spleen or gallbladder problems, menstrual problems, liver problems (such as … Milk thistle may affect how your liver processes this osteoporosis medication, causing higher levels of the drug in your bloodstream. Milk thistle is a natural herb with antioxidant and anti-inflammatory properties. Milk thistle has a range of potential health benefits due to its active ingredient, silymarin, which is an antioxidant. In 2010, a double-blind, placebo-controlled study compared the effects of milk thistle to the antidepressant Prozac (fluoxetine) in treating OCD (600 milligrams of milk thistle vs 30 milligrams of Prozac daily). One study has shown that milk thistle seed extract has estrogenic effects and effects on memory by estrogen. Simeprevir. Sleepiness, depression, personality changes, erratic behavior, psychosis, extreme fatigue, and all kinds of other symptoms can happen from excessive ammonia if not cleared out of the body, especially from the blood brain barrier. Milk thistle is a herbal drug that has been used for thousands of years to treat many different health problems. Milk thistle may reduce anxiety and improve depression. Some even claim that milk thistle is effective in treating depression and anxiety, but there’s not enough research to support these claims. Depression and anxiety are associated with increased risk of developing AD. As a woman prepares to end her childbearing years, hormonal changes take place. Milk thistle is generally considered safe when taken by mouth (1, 45). Milk Thistle seeds contain the highest concentrations of the active compound, silymarin. Milk thistle may have been combined with other plants or extracts in a specific preparation to treat these conditions. 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